Litaba

Mefuta ea pharmacokinetic e laoloang ke k'homphieutha

Ho sebelisa apharmacokineticea mohlala, k'homphieutha e tsoela pele ho bala tekanyo e lebeletsoeng ea mokuli ea lithethefatsi 'me e fana ka mofuta oa BET, ho fetola litekanyetso tsa ho kenngoa ha pompo, hangata ka nako ea metsotsoana e 10. Mehlala e nkiloe lithutong tsa pharmacokinetic tsa batho tse kileng tsa etsoa. Ka mananeo a lakatsehang target concentrations, thengaka e robatsange sebedisa sesebediswa ka mokgwa o tshoanang le mofenyi. Ho na le liphapang lipakeng tsa likhakanyo tse boletsoeng esale pele le tsa 'nete, empa tsena ha li na litlamorao tse kholo, ha feela maemo a nnete a le ka har'a fensetere ea kalafo ea moriana.

Pharmacokinetics ea mokuli le pharmacodynamics e fapana ho ea ka lilemo, tlhahiso ea pelo, lefu le phelang hammoho, tsamaiso ea lithethefatsi ka nako e le 'ngoe, mocheso oa' mele le boima ba mokuli. Lintlha tsena li phetha karolo ea bohlokoa tabeng ea ho khetha ho tsepamisa mohopolo.

Vaughan Tucker o ile a theha komporo ea pele e thusitseng kakaretso ea IV e thethefatsang methapo [CATIA]. Ea pele ea khoebophokotso e laoloang ke sepheoSesebelisoa e ne e le Diprufusor e hlahisitsoeng ke Astra Zeneca, e inehetseng ho tsamaiso ea propofol ka pel'a sering ea propofol e tlatsitsoeng pele e nang le khoele ea makenete ka lehlakoreng la eona. Litsamaiso tse ngata tse ncha li teng bakeng sa ho sebelisoa hona joale. Lintlha tsa mokuli tse kang boima ba 'mele, lilemo le bolelele li hlophisitsoe ka har'a pompo le software ea pompo, ka ho sebelisa papiso ea pharmacokinetic, ntle le ho laola le ho boloka litekanyetso tse loketseng tsa infusion, li bonts'a likhakanyo tse baloang le nako e lebelletsoeng ea ho hlaphoheloa.